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What Is the Main Cause of Eczema?

As with other auto-immune diseases, eczema flare-ups are caused by certain triggers – believed to be a combination of genetic and environmental factors. Just as asthma and other allergies involve a reaction to particular allergens that the body perceives as a threat, the over-reactive immune system of an eczema sufferer responds by producing the red, itchy, and inflamed skin symptoms common to most types of eczema. Studies have also shown that some people with eczema have a genetic mutation that affects the production of filaggrin, a protein that helps the very top layer of the skin maintain a healthy protective barrier.