The level of discomfort associated with hyperhidrosis treatment varies depending on the type of treatment. Topical treatments like prescription antiperspirants generally cause minimal discomfort, though some people may experience mild irritation or a stinging sensation. Botox injections, while generally well-tolerated, can cause mild pain or discomfort at the injection sites, similar to a pinprick, but this is usually brief and can be managed with a numbing cream.

Iontophoresis, which involves using a mild electrical current, is typically painless, though some individuals may feel a tingling sensation during the procedure. Surgical options, such as sympathectomy, involve more significant discomfort due to the invasive nature of the procedure, but this is managed with anesthesia and post-operative pain relief. Overall, most hyperhidrosis treatments are associated with only mild discomfort, and your healthcare provider can discuss pain management options with you if needed.