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Is Semaglutide Effective for Weight Loss?

Yes, semaglutide has shown promising results for weight loss in adults struggling with obesity or overweight and at least one weight-related comorbidity, such as type 2 diabetes or heart disease. Clinical trials involving semaglutide produced significant weight loss compared to a placebo group. On average, participants using semaglutide lost 5-10% of their body weight.

Semaglutide's effectiveness for weight loss is attributed to its mechanism of action. It mimics the effects of a natural gut hormone called glucagon-like peptide-1 (GLP-1), which plays a role in regulating appetite, blood sugar control, and satiety. By mimicking GLP-1, semaglutide helps you feel fuller for longer, leading to reduced calorie intake and ultimately contributing to weight loss.