How Does Semaglutide GLP-1 Work to Achieve Significant Weight Loss?
Semaglutide (a GLP-1 receptor agonist) is a Medication that revolutionized the medical approach to obesity by mimicking the action of the naturally occurring hormone Glucagon-Like Peptide-1 (GLP-1). This hormone is released in the gut after eating and performs two key functions that drive substantial, chronic weight loss.
First, Semaglutide GLP-1 acts directly on the Appetite centers of the brain, effectively suppressing the sensation of hunger and profoundly increasing feelings of fullness. This neuro-regulatory effect naturally leads to a significantly decreased daily calorie intake. Second, the medication dramatically slows the rate at which the stomach empties, ensuring food remains in the stomach longer and further prolonging the feeling of satiety after meals.
When used as an Essential adjunct to a comprehensive plan that includes a reduced-calorie diet and increased physical activity, clinical trials have shown that the weekly injectable, prescribed for adults with obesity or those who are overweight with comorbidities, can lead to an average weight loss of approximately 15% of initial body weight. This achievement marks Semaglutide GLP-1 as a powerful, necessary tool in the medical treatment of obesity as a chronic metabolic disease.
